Drugs for BPH 'might be protective' against Parkinson's disease

Large observational study confirms findings in animal models, researchers say

A class of drugs used to treat BPH may also be neuroprotective, a study shows.

tablets and pills in packets

In a large observational study, use of terazosin, doxazosin or alfuzosin was associated with a decreased risk of Parkinson's disease compared with the use of tamsulosin.

All four drugs are alpha-1-blockers and all except tamsulosin enhance glycolysis, the researchers noted in JAMA Neurology.

Glycolysis and mitochondrial function are known to be decreased in people with Parkinson’s disease.

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