Early aggressive fluid resuscitation not better for pancreatitis
Incidence of fluid overload higher, with no improvement in clinical outcomes compared with moderate fluid resuscitation
Early aggressive fluid resuscitation results in a higher incidence of fluid overload and does not improve clinical outcomes for patients presenting with acute pancreatitis, according to a study published in the 15 September issue of the New England Journal of Medicine.
Enrique de-Madaria, MD, PhD, from Dr Balmis General University Hospital in Alicante, Spain, and colleagues randomly assigned 249 patients at 18 centres who presented with acute pancreatitis to receive goal-directed aggressive or moderate resuscitation with lactated Ringer’s solution.
