Early faecal calprotectin change flags treatment response in UC: study
Researchers find reduced levels of the inflammatory marker post-induction is linked to lower risk of colectomy
Reduced faecal calprotectin levels following induction of biologics in ulcerative colitis more than quadruples the chance of clinical, endoscopic and histologic remission at one year, an analysis shows.
A post-induction faecal calprotectin (FCP) concentration at or under 250μg/g is also associated with a 40-70% lower risk of long-term colectomy and hospitalisation in patients with ulcerative colitis (UC), the US researchers say.
