Early tranexamic acid cuts deaths from brain injury

Time and severity of injury need to be taken into account, researchers say
Clare Pain
doctor looking at CT head

Early infusion of tranexamic acid in patients with mild to moderate traumatic brain injury saves lives, according to the results of a large clinical trial.

The trial, known as CRASH-3, was carried out in 175 hospitals across 29 countries, and randomised 12,737 adults presenting to EDs with traumatic brain injury to either infusion of the antifibrinolytic or saline placebo.