Early-onset lupus linked to higher risk of nephritis

Analysis of survival among a large British cohort suggests, however, that mortality is not increased in these patients

Patients diagnosed with SLE earlier in life, including those with juvenile-onset disease, are significantly more likely to develop lupus nephritis — but not necessarily to die from it, a study shows.

In a retrospective survival analysis of afflicted individuals, UK researchers investigated the factors influencing the risk of death in SLE over a period of 40 years.

They drew upon data for 496 patients treated at the University College London Hospital’s lupus clinic between 1979 and 2019, with

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