Few serious infections in babies exposed to non-TNF inhibitor biologics

The largest cohort yet examined of pregnant women with chronic inflammatory disease, researchers say

Children born to mothers with chronic inflammatory diseases, who took non-tumor-necrosis-factor (TNF) inhibitor biologics while pregnant, appear to be at low risk of developing serious infections, researchers say.

Pregnant woman

Canadian researchers examined the risk of serious infections in children born to mothers with chronic inflammatory diseases who took non-TNF inhibitor biologics or tofacitinib during pregnancy.

They compared the results with those for children not exposed to such treatments, as well as with children exposed to TNF inhibitors