First-in-class drug 'effective' in hypertrophic cardiomyopathy

The results show the benefit of disease-targeted therapy, researchers say

AusDoc brings you the latest news from the European Society of Cardiology Congress 2020.

Histologogy pic - cardiac myocytes

Mavacamten, a first-in-class cardiac myosin inhibitor, improves a range of outcomes in patients with obstructive hypertrophic cardiomyopathy, trial results show.

Results of the EXPLORER-HCM trial, presented at the European Society of Cardiology’s virtual congress (ESC 2020) this week compared outcomes of 123 people randomised to mavacamten (starting at 5mg) with 128

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