Fluctuating lipids in T2DM linked to microvascular morbidity

Greater visit-to-visit changes in cholesterol levels predict increased risk of certain complications, analysis shows

Greater lipid variability in patients with type 2 diabetes is associated with a nearly 60% increase in the risk of developing nephropathy or neuropathy compared to those with stable lipids, a study shows.

The findings, which implicate HDL cholesterol and triglycerides but not LDL cholesterol, highlight the importance of lipid-lowering therapy in this setting to stave off microvascular complications, Chinese researchers say.

In a post-hoc analysis of the ACCORD (Action to Control Cardiovascular Risk in Diabetes