Gabapentin ineffective for chronic pelvic pain, study finds

Randomised controlled trial results do not support off-label use, researchers say

Gabapentin doesn't relieve chronic pelvic pain in women any better than a placebo, according to study findings that suggest the drug should not be used off-label for this indication.

UK researchers randomised 306 women aged 18-50 who had chronic pelvic pain for at least three months to take either gabapentin (titrated to a maximum dose of 2700mg daily) or placebo for 16 weeks.

By the end of the intervention, there was no significant difference between gabapentin and placebo for mean numerical pain scores, mean change from baseline, or mean worst pain scores, the