Gene profiling predicts treatment response in refractory RA: study

UK researchers say their findings represent a 'paradigm shift' in precision medicine for affected patients
Reuters Health

Genetic profiling of synovial biopsies predicts lack of therapeutic response to biologics in patients with rheumatoid arthritis better than a model using only tissue pathology or clinical factors, a study shows.

UK researchers say their findings could pave the way for routine use of gene expression models for optimal selection of rituximab and tocilizumab treatment in this clinical setting.