Hallucinations and motor slowing ‘key to diagnosis’

Early-onset dementia with Lewy bodies is often misdiagnosed as Alzheimer's disease, researchers say
Reuters Health

Early-onset dementia with Lewy bodies has clear distinguishing characteristics that differentiate it from Alzheimer’s disease yet the condition is frequently misdiagnosed, researchers say.

Noting that dementia with Lewy bodies (DLB) is often taken to be Alzheimer’s disease (AD), researchers in Singapore set out to identify signs of differential diagnosis in patients younger than 65.

No longitudinal studies have been published on early-onset DLB, they added.

Neurologist Dr Simon Kang Seng Ting from Singapore General Hospital, and colleagues, investigated clinical features of 32 patients with early-onset DLB, 147 with late-onset DLB, and 363 with early-onset Alzheimer’s dementia in a case-control study.