Heart failure: Time to move on from NYHA ranking?

A US registry study finds that patient scoring of symptoms more accurately reflects their trajectory.
Clare Pain

A comprehensive patient-reported outcome scale correlates better with prognosis in heart failure than changes to New York Heart Association (NYHA) class, a study shows.

US researchers say serial assessments with a nuanced patient questionnaire reflects health status more accurately than clinician categorisation for longitudinal care of people with heart failure with reduced ejection fraction (HFrEF).

In a cohort study, they found improvement in the Kansas City Cardiomyopathy Questionnaire – Overall Summary Score (KCCQ-OS) was associated with lower risk of mortality but improvement in NYHA class had no such association.

Nearly 2900 patients with chronic HFrEF from the CHAMP-HF registry covering 145 US practices were included in the analysis.