How antihypertensive choice may influence cognitive decline

Medications that stimulate type-2 and type-4 angiotensin II receptors could be protective, a study suggests

Antihypertensives that stimulate rather than inhibit type-2 and type-4 angiotensin II receptors are associated with lower rates of cognitive impairment or probable dementia, US researchers say.

According to the secondary analysis of the SPRINT (Systolic Blood Pressure Intervention Trial) cohort, certain blood pressure-lowering regimens could play a protective role against cognitive decline.

“The main message for clinicians at this point is to emphasise the importance of achieving blood pressure targets as