How do fibroids affect cell-free DNA prenatal screening results?

An Australian study identifies the risk of false-positive results in a large cohort

A woman with uterine fibroids has an increased risk of receiving a false-positive result for a sub-chromosomal aberration on prenatal cell-free DNA testing, Australian researchers have found.


Such a result is more likely with growths that are large or numerous, according to findings from a study the authors say is the first comprehensive assessment of how fibroids affect the accuracy of non-invasive prenatal testing (NIPT). 

Patients can be reassured, however, that fibroids do not appear to interfere with