Hypofractionated radiotherapy following prostatectomy 'non-inferior'

The higher dose but shorter duration approach has similar levels of side-effects to conventional dosing, US researchers say

After prostate removal, use of fewer but higher doses of radiation does not increase long-term side effects or lead to lower quality of life compared with conventional radiation, according to clinical trial results.

Hypofractionated radiotherapy (HypoRT) "represents a new acceptable practice standard" for men receiving post-prostatectomy radiotherapy, said Dr Mark Buyyounouski of Stanford University, California, US, in a presentation of the results at the American Society for Radiation Oncology (ASTRO)