Immunosuppressant gets PBAC nod for ulcerative colitis

Listing would benefit patients who don't respond or are intolerant of other therapies

Subsidisation for the immunosuppressant ozanimod may soon be expanded to include moderate to severe ulcerative colitis, following a recommendation from the PBAC.

The committee said it was satisfied that the sponsor claim that the medication was non-inferior in efficacy and safety to infliximab was “likely to be reasonable”.

The drug — a selective sphingosine-1-phosphate receptor modulator that reduces circulating lymphocytes — is already subsidised for patients with relapsing-remitting MS.

It was approved by the TGA in 2020 for moderate to severely active ulcerative colitis in adults who have had an inadequate response, lost response, or were intolerant to either conventional or biological therapies.