Increased risk of cataracts with second-generation antipsychotics

Two antipsychotics in particular seem to be most associated with the condition

The use of second-generation antipsychotics in people with schizophrenia is associated with an increased risk of cataracts, researchers report.


Taiwanese researchers used registry data on more 13,000 patients with schizophrenia to compare cataract risk in patients taking first- and second-generation antipsychotics.

Among more than 10,000 matched patients (one-third taking first-generation drugs and two-thirds taking second-generation), those on second-generation therapy had a 59% greater risk of developing cataracts