Infections, low IgG 'common' in children on rituximab

Boston hospital study suggests corticosteroids compound the risk, researchers say.

A significant proportion of children and young adults with rheumatological diseases develop new-onset hypogammaglobulinaemia and infections following treatment with rituximab, US researchers report.

close up of young girl's hads - she's having an IV infusion

Furthermore, exposure to a pulse of corticosteroids appears to raise the odds of such complications, they say.

Harvard University researchers examined records for 85 children and young adults who were treated at Boston Children's