Isthmocele, not prior C-section, lowers IVF success rate: study

This negative association may be linked to accumulation of intrauterine cavity fluid, researchers say.

Isthmocele formation after a previous caesarean section — rather than the C-section itself — lowers the odds of a live birth in women undergoing IVF, research suggests.

Doctors from the University of Perugia in Italy say this association also appears to be “exacerbated” by the accumulation of intracavity fluid (ICF) before embryo transfer.