IVF: Artificial-cycle frozen-embryo transfer 'raises pre-eclampsia risk'

When possible, the natural ovulatory cycle should be used, researchers say

Artificial priming of the uterus with hormone therapy before transfer of a frozen embryo may increase the risk for pre-eclampsia and pregnancy-induced hypertension, a study shows.

freezing embryos

Using data from the national IVF registry of France, researchers evaluated maternal vascular morbidities in more than 68,000 singleton pregnancies.

These comprised more than 48,00 fresh-embryo transfers, 9500 natural-ovulatory-cycle frozen embryo transfers and nearly 10,400 artificial-cycle frozen-embryo transfers.