Leukaemia with CNS involvement tied to worse survival outcomes
CNS involvement 'should be treated as a negative prognostic marker', researchers say.
![](https://www.ausdoc.com.au/wp-content/uploads/2023/11/4x3_Neuron-system-disease_iStock-1434534146-300x225.jpg)
In adults with acute myeloid leukemia, those with CNS involvement have worse overall survival, according to a review in Leukemia Research.
US researchers conducted a systematic review and meta-analysis to characterise survival outcomes in patients with acute myeloid leukaemia (AML) with CNS involvement.