Major depression: Staying on antidepressants reduces relapse
Patients with chronic or recurrent major depressive disorder who have recovered while taking antidepressants would do best to stay on their medications, results of a clinical trial suggest.
Rates of recurrence over three years of follow-up were 48.5% in people who maintained antidepressant therapy, compared with 75.8% in those who were tapered off their medication, the US authors report in JAMA Psychiatry.