Metformin linked to worse cognition in older people

The researchers suggest vitamin B supplementation via fortified foods, but more research is needed

Metformin is associated with worse cognitive function in older adults, which could be explained by vitamin B deficiency, new research suggests.

Woman in her 70s

Northern Irish researchers investigated the relationship between hyperglycemia, metformin and vitamin B status in 4160 community-dwelling, dementia-free older people (mean age 74) participating in the Trinity, Ulster and Department of Agriculture (TUDA) study.