Methotrexate-biologic combo gives improved outcomes in early RA
Pooled data from 13 studies shows better scores with combination therapy

The combination of methotrexate with a biologic provides better outcomes than methotrexate monotherapy in adults with early rheumatoid arthritis, a study shows.
US researchers conducted a systematic review of 22 randomised controlled trials, including nearly 10,000 participants who had been diagnosed with RA for a year or less.