Mohs micrographic surgery may be an effective alternative to traditional wide-margin excision in some patients with early invasive melanoma, a large study suggests.

Yale University researchers looked at retrospective data for more than 70,000 patients (median age 57, 52% male, 97% Caucasian) with American Joint Committee on Cancer-8 stage I melanoma in the US National Cancer Database from 2004 to 2014.