Patients with inflammatory bowel disease (IBD), even those receiving biologics, are able to mount a significant immune response after getting mRNA COVID-19 vaccines, a study shows.

In an analysis of data from 48 IBD patients, of whom 85% were taking biologics at the time of vaccination with either the Pfizer-BioNTech or Moderna vaccines, all had positive antibody responses.

Furthermore, many achieved index levels that would qualify them for convalescent plasma donation, according to the report published in Gastroenterology.

All the patients were enrolled in the COVID-19 Therapeutic Infusion (CITI) study, an ongoing serosurvey of patients with IBD at the Icahn School of Medicine in New York City, US.