Mystery over two triple-negative breast cancer trial results

Does the type of paclitaxel make a difference to outcomes?
Medicom Staff writer
woman in pink top wearing pink ribbon to denote breast cancer

AusDoc brings you the latest news from the European Society for Medical Oncology virtual congress 2020.

Results of two similar trials in people with triple-negative breast cancer appear to be contradictory, with no obvious explanation for why this should be, a conference has been told.

Delegates at the European Society for Medical Oncology (ESMO) virtual congress 2020 first heard from Dr Leisha Emens of the University of Pittsburgh, US, who presented results for overall survival (OS) in the IMpassion130 phase 3 trial.

In this pivotal trial, 902 patients with untreated locally advanced or metastatic triple-negative breast cancer were randomised to nab-paclitaxel with either the programmed death ligand-1 (PD-L1) inhibitor, atezolizumab, or placebo.