NAFLD linked to increased risk of colorectal polyps

The effect may be specific to men and have implications for targeting screening, the researchers say

People with nonalcoholic fatty liver disease (NAFLD) might be at higher risk of colorectal polyps than their peers without the condition, with men being at most risk, a study suggests.

The systematic review and meta-analysis of 14 observational studies showed that a NAFLD diagnosis was associated with a 34% increase in odds of having a colorectal polyp, compared with people without the disease.

A similar analysis of six longitudinal cohort studies showed that people with NAFLD were 60% more likely to develop a colorectal polyp than people without