Nearly two-thirds of patients’ care changed post-amyloid PET

Results of amyloid PET scan change management in three out of five people with a prior diagnosis of dementia or mild cognitive impairment, US research shows.
“I was surprised by the magnitude of the effect we observed on management, which was more than double what we hypothesised,” says Dr Gil Rabinovici of the University of California, San Francisco.
Various PET ligands can detect amyloid-beta plaques, but whether amyloid PET improves health outcomes has remained unclear.
For their analysis, Dr Rabinovici and colleagues used data from the Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study of Medicare patients who met appropriate-use criteria for amyloid PET.