Neoadjuvant chemo ‘safe for locally advanced colon cancer’

More than half of patients demonstrate a histological response, investigators say
Clare Pain
Man having chemotherapy

Chemotherapy ahead of resection increases the likelihood of clear surgical margins in locally advanced colon cancer compared with surgery upfront, Australian researchers have found.

Their study, believed to be the first meta-analysis to examine the issue, also showed no increase in adverse outcomes, including toxicity.