Masked uncontrolled hypertension in patients with chronic kidney disease increases the risk of left ventricular hypertrophy and renal function decline, new research shows.

The findings suggest the need for greater use of ambulatory blood pressure monitoring (ABPM) in those with concomitant chronic kidney disease (CKD) and hypertension, regardless of their clinic blood pressure (BP) readings, according to Chinese clinicians.

Writing in JAMA Network Open, the researchers report findings from their study of 675 adults (mean age 51) with CKD not requiring dialysis to assess the prevalence and effect of night-time and day-night masked uncontrolled hypertension (MUCH).

Nearly two-thirds of the cohort were men and the average eGFR was 61.6ml/min/1.73m².