No evidence on MRI that intensive BP control cuts Alzheimer’s risk: study

Further results from the SPRINT MIND trial show a 'counterintuitive' association with decreased hippocampal volume

Intensive blood pressure control does not lead to clinically meaningful differences in brain imaging biomarkers of Alzheimer's disease on MRI, according to data from a US trial.

Blood pressure machine showing 148 over 94

In fact, for one biomarker — hippocampal volume — those in the intensive BP control arm fared worse, with a statistically significant decrease at the four-year follow-up.

The researchers evaluated MRI brain scans obtained at baseline and at follow-up in a subset of some 450 of the 9000-plus participants in the SPRINT MIND trial.