No gain from adding radiation for locally advanced endometrial cancer

Patients having chemotherapy alone have a better quality of life, researcher says

Supplementing chemotherapy with radiation fails to improve relapse-free survival in patients with locally advanced endometrial carcinoma, according to US research.

Radiation warning

The trial in more than 700 patients with stage III or IVA disease showed no difference in a composite of recurrence or death five years after enrolment between those randomised to receive chemotherapy plus radiotherapy and those who received chemotherapy alone.

All of the women in the GOG 258 trial had received a hysterectomy and bilateral salpingo