Novel combo pill 'promising' for endometriosis pain

A phase III trial shows improvement in dysmenorrhoea and non-menstrual pelvic pain along with lower opioid use

A novel combination therapy recently trialled in Australia shows promise for long-term treatment of endometriosis-associated pain, investigators say.

An international group of researchers, including reproductive health specialist Professor Neil Johnson from the Robinson Research Unit at the University of Adelaide, conducted two replicate phase III double-blinded trials to evaluate the once-daily oral treatment.

The pill combines a gonadotropin-releasing hormone (GnRH) antagonist, relugolix (40mg), with