Novel ‘quadpill’ for lowering BP trumps standard monotherapy: Aus trial

Researchers report on the QUARTET study of quarter-doses of four antihypertensives in one capsule
Medicom
Professor Clara Chow
Professor Clara Chow.

AusDoc brings you the latest news from the European Society of Cardiology Congress 2021.

Initiation of a quadruple combination of antihypertensive agents in quarter doses is a more effective way to bring blood pressure under control quickly than standard monotherapy with irbesartan, Australian cardiologists have shown.

Professor Clara Chow of the University of Sydney reported the results of the QUARTET study at the ESC Congress 2021, with the study simultaneously published in The Lancet.

The primary objective of QUARTET was to determine whether hypertension management starting with a single pill containing quarter-standard doses of four types of blood pressure lowering medicines – the ‘quadpill’ – was more effective than an approach starting with standard-dose monotherapy, she told delegates.