One biologic comes out on top in psoriatic arthritis trial

It's the first direct comparison of adalimumab and ixekizumab for the condition

The first head-to-head trial of two biologics for psoriatic arthritis suggests that, while adalimumab and ixekizumab are both effective, ixekizumab may have the edge in patients with active skin disease.

plaque psoriasis on an arm

The SPIRIT H2H clinical trial, funded by Eli Lilly and Company, which makes ixekizumab, compared 24-week results for 269 people randomised to the tumour necrosis factor (TNF) inhibitor, adalimumab, with 262 randomised to the interleukin 17A (IL-17A) antagonist, ixekizumab.

All patients were biologic-naïve and had active plaque

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