PCOS: Metformin might benefit overweight women using IVF

The drug is associated with fewer complications and a higher pregnancy rate, researchers say

Metformin treatment might benefit women with PCOS and a BMI of 26 or greater who are undergoing assisted reproduction, a meta-analysis suggests.

IVF: cells being manipulated udner a microscope

The medication is widely used in women with PCOS but its associations with outcomes of IVF or intracytoplasmic sperm injection and embryo transfer (ICSI-ET) remain controversial, the researchers note in JAMA Network Open.

Chinese researchers performed a meta-analysis of 12 randomised trials that enrolled 1123