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Pre-eclampsia tied to higher IHD and stroke risk in offspring, study shows

Researchers say the association was mainly independent of preterm and SGA birth, and may be partly explained by unmeasured familial factors

Offspring born to individuals with pre-eclampsia have an increased risk for ischaemic heart disease and stroke, according to a study published in JAMA Network Open.

Fen Yang, MD, from the Karolinska Institutet in Stockholm, Sweden and colleagues examined the association between maternal pre-eclampsia and risks for ischaemic heart disease (IHD) and stroke in offspring in a multinational population-based cohort study.

Data were obtained from live singleton births from Denmark (1973 to 2016), Finland (1987 to 2014), and Sweden (1973 to 2014) that were followed up until 31 December 2016 in Denmark and to 31 December 2014 in Finland and Sweden.

A total of 8,475,819 births were included (31.5%, 19.3% and 49.2% from Denmark, Finland and Sweden, respectively).

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