Psychotic disorders may raise risk for later dementia
Dementia risk is more than doubled compared with people without psychotic disorders
There is a substantial association between psychotic disorders and subsequent dementia, according to a review published in Psychological Medicine.
Sara El Miniawi, from University College London, and colleagues conducted a systematic literature review to identify longitudinal studies investigating non-affective psychotic disorders and subsequent dementia.
The researchers found that pooled data from 11 studies (about 13 million participants) showed non-affective psychotic disorders were associated with an increased risk for all-cause dementia (risk ratio, 2.52).
The associations were stronger in studies with shorter follow-up periods, conducted in non-European countries, published in 2020 or later, and in which ≥60% of the sample was female.
