Questions raised over effectiveness of faecal transplant for IBS

It is possible the mode of administration matters, researchers suggest

Faecal transplant for irritable bowel syndrome does not improve symptoms at 12 weeks, but route of administration may play a part, a systematic review and meta-analysis suggests.

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Pooling data from four randomised controlled trials with 254 participants, the US authors found no difference between people given a faecal microbiota transplant (FMT) and those given placebo.

At 12 weeks after transplant, 49% of those receiving donor faecal material reported an improvement of global IBS symptoms, compared with 51% of those assigned to placebo, the

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