Radiotherapy for rectal cancer linked to risk for gynaecological malignancy

Large study of US data shows increased risk of later uterine and ovarian cancers

Women who receive radiotherapy for rectal cancer may be at an increased risk of uterine and ovarian cancer, a US study suggests.

radiation sign

In an analysis of information from the Surveillance, Epidemiology and End Results (SEER) database on more than 20,000 US female patients diagnosed with rectal cancer, researchers found the treatment was associated with a three-fold increased risk of subsequent uterine cancer and a two-fold increased risk of ovarian cancer.

Chinese researchers used information from SEER from 1973 to 2015, including women

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