Retinal imaging may predict familial Alzheimer’s disease
Study in a Colombian kindred with a dominant mutation showed pathology visible in patients' 30s
Retinal alterations visible with optical coherence tomography (OCT) in carriers of familial Alzheimer’s disease may presage cognitive decline, according to a cross-sectional study.
US researchers studied 10 carriers of the presenilin 1 (PSEN1) E280A mutation who were cognitively unimpaired and 10 healthy family members without the mutation.