Review clarifies infection risk with anti-TNFs for psoriasis

Serious infection is not more likely and overall infection risk may depend on patient characteristics and the specific agent, researchers say

Use of TNF inhibitors in patients with psoriatic disease is not associated with increased risk of serious infections, according to the largest review of the literature to date.

Although the likelihood of overall infection was elevated in comparison with placebo, data from more than 15,000 adults with psoriasis or psoriatic arthritis suggests it is a tolerable risk, researchers say.