Review reveals top drugs for weight loss
But the leading agents also have the most challenging profiles for adverse events, researchers say
Phentermine-topiramate and glucagon-like peptide-1 receptor agonists are the most effective pharmacotherapies for adults with overweight and obesity, leading to bodyweight reductions of 6-11%, a large review shows.
The findings should facilitate optimal, evidence-based decision-making for patients and clinicians when considering weight loss interventions, the Chinese-led researchers say, although they note the most effective agent is approved for the indication only in the US.
