Rheumatologists asked to be alert to acromegaly

Measurement of IGF-1 can help with early diagnosis, says leading endocrinologist

A new consensus update on the diagnosis and treatment of acromegaly emphasises aggressive treatment of comorbidities, including bone and joint disorders.

blood test

"Acromegaly is associated with very high, common comorbidities — mainly cardiovascular, hypertension, diabetes, sleep apnoea and rheumatological," says senior author Professor Shlomo Melmed, of Cedars-Sinai Medical Centre in California, US.

"The cause of death in these patients is really due to exacerbations of those comorbidities," he said.

"If growth hormone levels are