Rivaroxaban ‘beneficial’ after revascularisation for claudication

Patients who undergo lower extremity revascularisation for claudication and then have rivaroxaban have fewer major cardiovascular events than if they take placebo, researchers report.
The results come from a post-hoc sub-analysis of the VOYAGER-PAD trial, looking just at data for 5031 patients who had their revascularisation procedure for claudication.
VOYAGER-PAD (The Vascular Outcomes Study of Acetylsalicylic Acid Along with Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease)) trial had shown a reduction of major cardiovascular events in patients who had undergone lower extremity revascularisation (LER) either for critical limb-threatening ischaemia or claudication when they were treated with rivaroxaban.
Just as in the overall trial, the primary outcome for the sub-analysis was a composite score of major cardiovascular events at three years, delegates to the American Heart Association Scientific Sessions 2021 virtual meeting were told.