Romosozumab 'safe and effective' in women with osteoporosis and CKD

A post-hoc analysis shows the biologic reduced fracture risk with similar adverse event rates across a range of renal function levels

Postmenopausal women with comorbid osteoporosis and mild-to-moderate chronic kidney disease can safely be prescribed romosozumab, US-led researchers say.

Their findings suggest that the monoclonal antibody remains highly effective across varying levels of renal function down to an eGFR of 30mL/min/1.73m2.

The findings are “reassuring”, the authors said, given the two-to-threefold greater risk of fracture and death in patients with both conditions compared to the general

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