Routine screening MRI for spinal cord compression in prostate cancer 'not warranted'

The first multi-centre RCT in men with castration-resistant metastatic prostate cancer finds there's no survival benefit with the intervention

Routine screening MRI and pre-emptive treatment for spinal cord compression in patients with asymptomatic castration-resistant prostate cancer is not justified, according to UK-based researchers.

In an open-label, randomised controlled trial, they found spinal MRI, followed by treatment as needed, did not significantly reduce the risk of progression from radiological spinal cord compression (rSCC) to clinical SCC (cSCC) compared with no screening.

"MRI screen-detected early rSCC does not