Salpingo-oophorectomy after breast cancer surgery cuts mortality in decades-long study

Overall survival improvements were ‘most evident’ in patients with the BRCA1 pathogenic variant and triple-negative disease.

Prophylactic salpingo-oophorectomy at the time of breast cancer surgery in patients with the BRCA1 and BRCA2 pathogenic variants cuts the long-term risk of death by 60%, Italian doctors say.

Results from their decades-long retrospective cohort study back the importance of offering the risk-reducing procedure to those with invasive breast cancer and who carry the genetic mutations.