Semaglutide cuts need for diuretics in HFpEF, researchers say
The medication also has a beneficial effect on change in body weight across diuretic use categories.
Semaglutide reduces the need for loop diuretics and has positive effects on symptoms, physical limitations and body weight in patients with heart failure with preserved ejection fraction, regardless of diuretic use, according to research presented at the European Society of Cardiology Heart Failure 2024 congress.
Dr Kavita Sharma, from the Johns Hopkins University School of Medicine in Baltimore, US, and colleagues used data from 1145 adults with obesity-related heart failure with preserved ejection fraction (HFpEF) who were randomly assigned to once-weekly semaglutide or placebo for 52 weeks.
